This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Fraser, M. Search for Related Content Social Bookmarking                         What's this?

Material Theory

Duration and the Serotonin Hypothesis of Depression

Goldsmiths College, University of London

This article addresses the serotonin hypothesis of depression, as it was formulated in clinical and laboratory experiments during the 1950s. In the first instance I argue that the `challenge' posed by patients' subjectivities in clinical investigations into the potentially anti-depressant drug iproniazid was not solely due to the tensions generated by the subject/object dichotomy, but to an excess that exceeds the properties of the objects of the experiment, as well as its requirements and conditions. I then suggest that the serotonin hypothesis too is possessed of an excess, and that this can be understood in terms of a real (actual and virtual) existence in duration. By exploiting the notions of the event and of duration, I offer an under-standing of the hypothesis that pertains not to reduction, reproducibility and sameness, but to differentiation, innovation and creation.

Key Words: duration • event objects • relations • serotonin hypothesis of depression • time

Theory, Culture & Society, Vol. 20, No. 5, 1-26 (2003)
DOI: 10.1177/02632764030205001


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?